- 产品信息
商品描述
靶点-Target
FKB1B
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
11kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein AA range: 1-50
特异性
FKB1B Polyclonal Antibody detects endogenous levels of protein.
基因名称
FKBP1B FKBP12.6 FKBP1L FKBP9 OTK4
蛋白名称
Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B) (12.6 kDa FK506-binding protein) (12.6 kDa FKBP) (FKBP-12.6) (FK506-binding protein 1B) (FKBP-1B) (Immunophilin FKBP12.6) (Rotamase) (h-FKBP-12)
Organism-1
Human
基因ID-1
2281
SwissProt-1
P68106
Organism-2
Mouse
SwissProt-2
Q9Z2I2
Organism-3
Rat
SwissProt-3
P97534
背景
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Sarcoplasmic reticulum .





