FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CFC1B
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
24kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
CFC1B Polyclonal Antibody detects endogenous levels of protein.
基因名称
CFC1B
蛋白名称
Cryptic family protein 1B
Organism-1
Human
基因ID-1
653275
SwissProt-1
P0CG36
背景
disease:Defects in CFC1 are a cause of conotruncal heart malformations (CTHM) [MIM:217095]. CTHM consist of cardiac outflow tract defects, such as tetralogy of Fallot, pulmonary atresia, double-outlet right ventricle, truncus arteriosus communis, and aortic arch anomalies.,disease:Defects in CFC1 are a cause of transposition of the great arteries, dextro-looped (DTGA) [MIM:608808]. The more common form of DTGA, consists of complete inversion of the great vessels, so that the aorta incorrectly arises from the right ventricle and the pulmonary artery incorrectly arises from the left ventricle. This creates completely separate pulmonary and systemic circulatory systems, an arrangement that is incompatible with life. Patients often have atrial and/or ventricular septal defects or other types of shunting that allow some mixing between the circulations in order to support life minimally, but surgical intervention is always required.,disease:Defects in CFC1 are a cause of visceral heterotaxy (HTX2) [MIM:605376]. HTX2 is an autosomal form of visceral heterotaxy (HTX). HTX is characterized by a variable group of congenital anomalies that include complex cardiac malformations and situs inversus or situs ambiguus.,function:Involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation.,PTM:N-glycosylated.,similarity:Contains 1 EGF-like domain.,
细胞定位
Secreted .
