- 产品信息
商品描述
靶点-Target
HTRA1
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
52kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
HTRA1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
HTRA1 HTRA PRSS11
蛋白名称
Serine protease HTRA1 (High-temperature requirement A serine peptidase 1) (L56) (Serine protease 11)
Organism-1
Human
基因ID-1
5654
SwissProt-1
Q92743
Organism-2
Mouse
SwissProt-2
Q9R118
Organism-3
Rat
SwissProt-3
Q9QZK5
背景
This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane . Secreted . Cytoplasm, cytosol . Predominantly secreted (PubMed:15208355). Also found associated with the plasma membrane (PubMed:21297635). .





