- 产品信息
商品描述
靶点-Target
NEUS
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
45kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
NEUS Polyclonal Antibody detects endogenous levels of protein.
基因名称
SERPINI1 PI12
蛋白名称
Neuroserpin (Peptidase inhibitor 12) (PI-12) (Serpin I1)
Organism-1
Human
基因ID-1
5274
SwissProt-1
Q99574
Organism-2
Mouse
SwissProt-2
O35684
Organism-3
Rat
SwissProt-3
Q9JLD2
背景
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Secreted . Cytoplasmic vesicle, secretory vesicle lumen . Perikaryon .





