FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
KIRR2
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
77kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
KIRR2 Polyclonal Antibody detects endogenous levels of protein.
基因名称
KIRREL2 NEPH3 UNQ5827/PRO19646
蛋白名称
Kin of IRRE-like protein 2 (Kin of irregular chiasm-like protein 2) (Nephrin-like protein 3)
Organism-1
Human
基因ID-1
84063
SwissProt-1
Q6UWL6
Organism-2
Mouse
SwissProt-2
Q7TSU7
背景
This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. [provided by RefSeq, Jul 2016],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Localized along the sites of the cell contacts. Colocalizes with E-Cadherin and beta-catenin. .
