- 产品信息
商品描述
靶点-Target
TNR8
反应性
Human,Rat,Mouse
应用
WB,IHC,IF,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
65kD
推荐稀释比
WB 1:500-2000;IHC: 50-200;ELISA 1:5000-20000;IF 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
TNR8 Polyclonal Antibody detects endogenous levels of protein.
基因名称
TNFRSF8 CD30 D1S166E
蛋白名称
Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30)
Organism-1
Human
基因ID-1
943
SwissProt-1
P28908
Organism-2
Mouse
SwissProt-2
Q60846
Organism-3
Rat
SwissProt-3
P97525
背景
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
细胞定位
[Isoform 1]: Cell membrane ; Single-pass type I membrane protein .; [Isoform 2]: Cytoplasm .





