FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PKN3
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
97kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
PKN3 Polyclonal Antibody detects endogenous levels of protein.
基因名称
PKN3 PKNBETA
蛋白名称
Serine/threonine-protein kinase N3 (Protein kinase PKN-beta) (Protein-kinase C-related kinase 3)
Organism-1
Human
基因ID-1
29941
SwissProt-1
Q6P5Z2
Organism-2
Mouse
SwissProt-2
Q8K045
背景
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation.,function:Contributes to invasiveness in malignant prostate cancer.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 REM (Hr1) repeats.,subcellular location:Nuclear and perinuclear Golgi region.,tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.,
细胞定位
Nucleus . Cytoplasm, perinuclear region . Nuclear and perinuclear Golgi region.
