- 产品信息
商品描述
靶点-Target
KPCD3
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
97kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
KPCD3 Polyclonal Antibody detects endogenous levels of protein.
基因名称
PRKD3 EPK2 PRKCN
蛋白名称
Serine/threonine-protein kinase D3 (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)
Organism-1
Human
基因ID-1
23683
SwissProt-1
O94806
Organism-2
Mouse
SwissProt-2
Q8K1Y2
背景
This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking. [provided by RefSeq, Jan 2015],
细胞定位
Cytoplasm . Membrane . Translocation to the cell membrane is required for kinase activation.





