KPCD3 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2604033

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商品描述
  • 靶点-Target

    KPCD3

  • 反应性

    Human,Mouse

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    97kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:5000-20000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from part region of human protein

  • 特异性

    KPCD3 Polyclonal Antibody detects endogenous levels of protein.

  • 基因名称

    PRKD3 EPK2 PRKCN

  • 蛋白名称

    Serine/threonine-protein kinase D3 (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu)

  • Organism-1

    Human

  • 基因ID-1

    23683

  • SwissProt-1

    O94806

  • Organism-2

    Mouse

  • SwissProt-2

    Q8K1Y2

  • 背景

    This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking. [provided by RefSeq, Jan 2015],

  • 细胞定位

    Cytoplasm . Membrane . Translocation to the cell membrane is required for kinase activation.