FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NUAK2
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
69kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
NUAK2 Polyclonal Antibody detects endogenous levels of protein.
基因名称
NUAK2 OMPHK2 SNARK
蛋白名称
NUAK family SNF1-like kinase 2 (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)
Organism-1
Human
基因ID-1
81788
SwissProt-1
Q9H093
Organism-2
Mouse
SwissProt-2
Q8BZN4
Organism-3
Rat
SwissProt-3
Q66HE5
背景
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-208 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.,PTM:Autophosphorylated in vitro.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.,similarity:Contains 1 protein kinase domain.,
细胞定位
nucleus,cytoplasm,nuclear speck,
