FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MCM9
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
125kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein. AA range 220-240
特异性
MCM9 Polyclonal Antibody detects endogenous levels of protein.
基因名称
MCM9 C6orf61 MCMDC1
蛋白名称
DNA helicase MCM9 (hMCM9) (Mini-chromosome maintenance deficient domain-containing protein 1) (Minichromosome maintenance 9)
Organism-1
Human
基因ID-1
254394
SwissProt-1
Q9NXL9
Organism-2
Mouse
SwissProt-2
Q2KHI9
Organism-3
Rat
SwissProt-3
F1M5F3
背景
The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1. [provided by RefSeq, Nov 2010],
细胞定位
Nucleus . Chromosome . Colocalizes to nuclear foci with RPA1 following DNA damage (PubMed:23401855). Localizes to double-stranded DNA breaks (PubMed:23401855). Recruited to chromatin by MSH2 (PubMed:26300262). .
