FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CC14B
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
54kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein AA range: 407-457
特异性
CC14B Polyclonal Antibody detects endogenous levels of protein.
基因名称
CDC14B
蛋白名称
Dual specificity protein phosphatase CDC14B (CDC14 cell division cycle 14 homolog B)
Organism-1
Human
基因ID-1
8555
SwissProt-1
O60729
Organism-2
Mouse
SwissProt-2
Q6PFY9
背景
cell division cycle 14B(CDC14B) Homo sapiens The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus, nucleolus. Nucleus, nucleoplasm. Following DNA damage, translocates from the nucleolus to the nucleoplasm and interacts with FZR1/CDH1.
