- 产品信息
商品描述
靶点-Target
KDM4D
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
57kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 400-480
特异性
KDM4D Polyclonal Antibody detects endogenous levels of protein.
基因名称
KDM4D JHDM3D JMJD2D
蛋白名称
Lysine-specific demethylase 4D (JmjC domain-containing histone demethylation protein 3D) (Jumonji domain-containing protein 2D)
Organism-1
Human
基因ID-1
55693
SwissProt-1
Q6B0I6
Organism-2
Mouse
SwissProt-2
Q3U2K5
Organism-3
Rat
SwissProt-3
A1A5Q5
背景
caution:It is uncertain whether Met-1 or Met-4 is the initiator.,cofactor:Binds 1 Fe(2+) ion per subunit.,function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.,similarity:Belongs to the JHDM3 histone demethylase family.,similarity:Contains 1 JmjC domain.,similarity:Contains 1 JmjN domain.,
细胞定位
Nucleus .





