- 产品信息
商品描述
靶点-Target
UIMC1
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
79kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
UIMC1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
UIMC1 RAP80 RXRIP110
蛋白名称
BRCA1-A complex subunit RAP80 (Receptor-associated protein 80) (Retinoid X receptor-interacting protein 110) (Ubiquitin interaction motif-containing protein 1)
Organism-1
Human
基因ID-1
51720
SwissProt-1
Q96RL1
Organism-2
Mouse
SwissProt-2
Q5U5Q9
Organism-3
Rat
SwissProt-3
Q5PQK4
背景
ubiquitin interaction motif containing 1(UIMC1) Homo sapiens This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
细胞定位
Nucleus . Localizes at sites of DNA damage at double-strand breaks (DSBs).





