FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NFX1
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
123kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 80-160
特异性
NFX1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
NFX1 NFX2
蛋白名称
Transcriptional repressor NF-X1 (Nuclear transcription factor, X box-binding protein 1)
Organism-1
Human
基因ID-1
4799
SwissProt-1
Q12986
Organism-2
Mouse
SwissProt-2
B1AY10
背景
MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus.
