- 产品信息
商品描述
靶点-Target
TM1L1
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
52kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
TM1L1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
TOM1L1 SRCASM
蛋白名称
TOM1-like protein 1 (Src-activating and signaling molecule protein) (Target of Myb-like protein 1)
Organism-1
Human
基因ID-1
10040
SwissProt-1
O75674
Organism-2
Mouse
SwissProt-2
Q923U0
Organism-3
Rat
SwissProt-3
F1LM81
背景
function:Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promotes FYN activation, possibly by disrupting intramolecular SH3-dependent interactions.,PTM:Phosphorylated on tyrosines by FYN (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TOM1 family.,similarity:Contains 1 GAT domain.,similarity:Contains 1 VHS domain.,subunit:Interacts with FYN, GRB2 and PIK3R1 when phosphorylated.,
细胞定位
Golgi apparatus, Golgi stack. Endosome membrane . Cytoplasm . Membrane ; Peripheral membrane protein ; Cytoplasmic side . A small proportion is membrane-associated. .





