FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SH3B4
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
105kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein around amino acid site 145
特异性
SH3B4 Polyclonal Antibody detects endogenous levels of protein.
基因名称
SH3BP4 BOG25 EHB10 TTP
蛋白名称
SH3 domain-binding protein 4 (EH-binding protein 10) (Transferrin receptor-trafficking protein)
Organism-1
Human
基因ID-1
23677
SwissProt-1
Q9P0V3
Organism-2
Mouse
SwissProt-2
Q921I6
Organism-3
Rat
SwissProt-3
Q9JJS5
背景
This gene encodes a protein with 3 Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. This protein is involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of a specific protein receptor. [provided by RefSeq, Jul 2008],
细胞定位
Membrane, clathrin-coated pit. Cytoplasmic vesicle, clathrin-coated vesicle. Nucleus . Specifically associated with transferrin receptor-containing clathrin-coated pits and clathrin-coated vesicles. May also localize to the nucleus.
