- 产品信息
商品描述
靶点-Target
SH2D3
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
94kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
SH2D3 Polyclonal Antibody detects endogenous levels of protein.
基因名称
SH2D3C NSP3 UNQ272/PRO309/PRO34088
蛋白名称
SH2 domain-containing protein 3C (Novel SH2-containing protein 3)
Organism-1
Human
基因ID-1
10044
SwissProt-1
Q8N5H7
Organism-2
Mouse
SwissProt-2
Q9QZS8
背景
This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
细胞定位
Cytoplasm . Cell membrane ; Peripheral membrane protein . Cell projection, axon . Cell projection, ruffle membrane . Associated with the membrane when EGF-stimulated (By similarity). Expressed at the cortical actin ring in B cells (By similarity). .; [Isoform 1]: Cell membrane ; Peripheral membrane protein .





