FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
WNK4
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
136kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
WNK4 Polyclonal Antibody detects endogenous levels of protein.
基因名称
WNK4 PRKWNK4
蛋白名称
Serine/threonine-protein kinase WNK4 (Protein kinase lysine-deficient 4) (Protein kinase with no lysine 4)
Organism-1
Human
基因ID-1
65266
SwissProt-1
Q96J92
Organism-2
Mouse
SwissProt-2
Q80UE6
Organism-3
Rat
SwissProt-3
Q7TPK6
背景
This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.[provided by RefSeq, Sep 2009],
细胞定位
Cell junction, tight junction . Present exclusively in intercellular junctions in the distal convoluted tubule and in both the cytoplasm and intercellular junctions in the cortical collecting duct. WNK4 is part of the tight junction complex. .
