FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
VRK1
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
43kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
VRK1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
VRK1
蛋白名称
Serine/threonine-protein kinase VRK1 (Vaccinia-related kinase 1)
Organism-1
Human
基因ID-1
7443
SwissProt-1
Q99986
Organism-2
Mouse
SwissProt-2
Q80X41
背景
vaccinia related kinase 1(VRK1) Homo sapiens This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . Dispersed throughout the cell but not located on mitotic spindle or chromatids during mitosis.
