RHG44 Polyclonal Antibody

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¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2603389

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商品描述
  • 靶点-Target

    RHG44

  • 反应性

    Human,Mouse

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    89kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:5000-20000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human protein . at AA range: 430-510

  • 特异性

    RHG44 Polyclonal Antibody detects endogenous levels of protein.

  • 基因名称

    ARHGAP44 KIAA0672 RICH2

  • 蛋白名称

    Rho GTPase-activating protein 44 (NPC-A-10) (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2)

  • Organism-1

    Human

  • 基因ID-1

    9912

  • SwissProt-1

    Q17R89

  • Organism-2

    Mouse

  • SwissProt-2

    Q5SSM3

  • 背景

    function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1.,sequence caution:Translation N-terminally extended.,similarity:Contains 1 BAR domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Highly expressed in brain. Expressed at weak level in other tissues.,

  • 细胞定位

    Cell projection, dendritic spine . Recycling endosome . Cell junction, synapse, presynapse . Cell projection, dendrite . In CA1 hippocampal synapses, detected at both presynaptic and postsynaptic sites (By similarity). Located in convoluted dendritic plasma membrane sections enriched in polymerized actin and myosin (patches) along dendrites where often emerge filopodia (By similarity). .