RELN Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2603368

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商品描述
  • 靶点-Target

    RELN

  • 反应性

    Human,Rat

  • 应用

    IHC,IF

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    380kD

  • 推荐稀释比

    IHC 1:50-300;IF 1:50-200

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human protein . at AA range: 270-350

  • 特异性

    RELN Polyclonal Antibody detects endogenous levels of protein.

  • 基因名称

    RELN

  • 蛋白名称

    Reelin (EC 3.4.21.-)

  • Organism-1

    Human

  • 基因ID-1

    5649

  • SwissProt-1

    P78509

  • Organism-2

    Mouse

  • SwissProt-2

    Q60841

  • Organism-3

    Rat

  • SwissProt-3

    P58751

  • 背景

    This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Secreted, extracellular space, extracellular matrix .