- 产品信息
商品描述
靶点-Target
RELN
反应性
Human,Rat
应用
IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
380kD
推荐稀释比
IHC 1:50-300;IF 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 270-350
特异性
RELN Polyclonal Antibody detects endogenous levels of protein.
基因名称
RELN
蛋白名称
Reelin (EC 3.4.21.-)
Organism-1
Human
基因ID-1
5649
SwissProt-1
P78509
Organism-2
Mouse
SwissProt-2
Q60841
Organism-3
Rat
SwissProt-3
P58751
背景
This gene encodes a large secreted extracellular matrix protein thought to control cell-cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two transcript variants encoding distinct isoforms have been identified for this gene. Other transcript variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Secreted, extracellular space, extracellular matrix .





