FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
RB33B
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
25kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 100-180
特异性
RB33B Polyclonal Antibody detects endogenous levels of protein.
基因名称
RAB33B
蛋白名称
Ras-related protein Rab-33B
Organism-1
Human
基因ID-1
83452
SwissProt-1
Q9H082
Organism-2
Mouse
SwissProt-2
O35963
背景
This gene encodes a small GTP-binding protein of the Rab GTPase family, whose members function in vesicle transport during protein secretion and endocytosis. Rab GTPases are active, membrane-associated proteins that recruit effector proteins in the GTP-bound state and inactive cytosolic proteins when in a GDP-bound state. The protein encoded by this gene is ubiquitously expressed and has been implicated in Golgi to endoplasmic reticulum cycling of Golgi enzymes. In addition, this protein regulates Golgi homeostasis and coordinates intra-Golgi retrograde trafficking. Allelic variants in this gene have been associated with Dyggve-Melchior-Clausen syndrome and Smith-McCort dysplasia 2, which are autosomal recessive spondyloepimetaphyseal dysplasias characterized by skeletal abnormalities. [provided by RefSeq, Sep 2016],
细胞定位
Golgi apparatus membrane ; Lipid-anchor . Golgi apparatus, cis-Golgi network . Under starvation conditions punctate RAB33B-positive structures are often observed in the cytoplasm. .
