- 产品信息
商品描述
靶点-Target
HCN4
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
132kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 600-680
特异性
HCN4 Polyclonal Antibody detects endogenous levels of protein.
基因名称
HCN4
蛋白名称
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Organism-1
Human
基因ID-1
10021
SwissProt-1
Q9Y3Q4
Organism-2
Mouse
SwissProt-2
O70507
Organism-3
Rat
SwissProt-3
Q9JKA7
背景
This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008],
细胞定位
Cell membrane ; Multi-pass membrane protein .





