FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
AT2B3
反应性
Human,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
134kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 140-220
特异性
AT2B3 Polyclonal Antibody detects endogenous levels of protein.
基因名称
ATP2B3
蛋白名称
Plasma membrane calcium-transporting ATPase 3 (PMCA3) (Plasma membrane calcium ATPase isoform 3) (Plasma membrane calcium pump isoform 3)
Organism-1
Human
基因ID-1
492
SwissProt-1
Q16720
Organism-3
Rat
SwissProt-3
Q64568
背景
The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 3. Alternatively spliced tran
细胞定位
Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, presynaptic cell membrane ; Multi-pass membrane protein . Localized at parallel fiber terminals. .
