- 产品信息
商品描述
靶点-Target
PA21B
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
16kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 70-150
特异性
PA21B Polyclonal Antibody detects endogenous levels of protein.
基因名称
PLA2G1B PLA2 PLA2A PPLA2
蛋白名称
Phospholipase A2 (Group IB phospholipase A2) (Phosphatidylcholine 2-acylhydrolase 1B)
Organism-1
Human
基因ID-1
5319
SwissProt-1
P04054
Organism-2
Mouse
SwissProt-2
Q9Z0Y2
Organism-3
Rat
SwissProt-3
P04055
背景
This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response. [provided by RefSeq, Aug 2013],
细胞定位
Secreted . Secreted from pancreatic acinar cells in its inactive form.





