FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PACS1
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
105kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 400-480
特异性
PACS1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
PACS1 KIAA1175
蛋白名称
Phosphofurin acidic cluster sorting protein 1 (PACS-1)
Organism-1
Human
基因ID-1
55690
SwissProt-1
Q6VY07
Organism-2
Mouse
SwissProt-2
Q8K212
Organism-3
Rat
SwissProt-3
O88588
背景
This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008],
细胞定位
Golgi apparatus, trans-Golgi network . Localizes in the perinuclear region, probably the TGN. .
