PHX2A Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2603195

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商品描述
  • 靶点-Target

    PHX2A

  • 反应性

    Human,Rat,Mouse

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    31kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:5000-20000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human protein . at AA range: 210-290

  • 特异性

    PHX2A Polyclonal Antibody detects endogenous levels of protein.

  • 基因名称

    PHOX2A ARIX PMX2A

  • 蛋白名称

    Paired mesoderm homeobox protein 2A (ARIX1 homeodomain protein) (Aristaless homeobox protein homolog) (Paired-like homeobox 2A)

  • Organism-1

    Human

  • 基因ID-1

    401

  • SwissProt-1

    O14813

  • Organism-2

    Mouse

  • SwissProt-2

    Q62066

  • Organism-3

    Rat

  • SwissProt-3

    Q62782

  • 背景

    paired like homeobox 2a(PHOX2A) Homo sapiens The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Nucleus .