FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NRX1B
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
48kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 260-340
特异性
NRX1B Polyclonal Antibody detects endogenous levels of protein.
基因名称
NRXN1
蛋白名称
Neurexin-1-beta (Neurexin I-beta)
Organism-1
Human
基因ID-1
9378
SwissProt-1
P58400
Organism-2
Mouse
SwissProt-2
P0DI97
Organism-3
Rat
SwissProt-3
Q63373
背景
alternative products:A number of isoforms are produced by alternative promoter usage including the alpha-type (shown here) and beta-type (AC P58400) isoforms which differ in their N-terminus. Additional isoforms may be produced by alternative splicing,alternative products:A number of isoforms, alpha-type (AC Q9ULB1) and beta-type (shown here), are produced by alternative promoter usage. Beta-type isoforms differ from alpha-type isoforms in their N-terminus,function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling.,function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.,PTM:Highly O-glycosylated and minor N-glycosylated.,PTM:N- and O-glycosylated.,similarity:Belongs to the neurexin family.,similarity:Contains 1 laminin G-like domain.,similarity:Contains 3 EGF-like domains.,similarity:Contains 6 laminin G-like domains.,subunit:The cytoplasmic C-terminal region binds to CASK, CASKIN1 and APBA1. The laminin G-like domain 2 binds to NXPH1. Specific isoforms bind to alpha-dystroglycan and to alpha-latroxin. Interacts with SYT13 and SYTL1.,subunit:The cytoplasmic C-terminal region binds to CASK. Isoforms Beta 4b bind neuroligins NLGN1, NLGN2 and NLGN3, alpha-dystroglycan and alpha-latrotoxin.,tissue specificity:Heart and brain.,
细胞定位
Cell junction, synapse, presynaptic cell membrane ; Single-pass type I membrane protein .
