- 产品信息
商品描述
靶点-Target
UNC5B
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
103kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 350-430
特异性
UNC5B Polyclonal Antibody detects endogenous levels of protein.
基因名称
UNC5B P53RDL1 UNC5H2 UNQ1883/PRO4326
蛋白名称
Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1)
Organism-1
Human
基因ID-1
219699
SwissProt-1
Q8IZJ1
Organism-2
Mouse
SwissProt-2
Q8K1S3
Organism-3
Rat
SwissProt-3
O08722
背景
This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Membrane raft . Associated with lipid rafts. .





