- 产品信息
商品描述
靶点-Target
SIR4
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
34kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
SIR4 Polyclonal Antibody detects endogenous levels of protein.
基因名称
SIRT4 SIR2L4
蛋白名称
NAD-dependent protein deacetylase sirtuin-4 (NAD-dependent ADP-ribosyltransferase sirtuin-4) (Regulatory protein SIR2 homolog 4) (SIR2-like protein 4)
Organism-1
Human
基因ID-1
23409
SwissProt-1
Q9Y6E7
Organism-2
Mouse
SwissProt-2
Q8R216
背景
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion matrix .





