FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MYO15
反应性
Human,Mouse
应用
IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
388kD
推荐稀释比
IHC 1:50-300;IF 1:50-200
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 2990-3070
特异性
MYO15 Polyclonal Antibody detects endogenous levels of protein.
基因名称
MYO15A MYO15
蛋白名称
Unconventional myosin-XV (Unconventional myosin-15)
Organism-1
Human
基因ID-1
51168
SwissProt-1
Q9UKN7
Organism-2
Mouse
SwissProt-2
Q9QZZ4
背景
This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Cell projection, stereocilium . Cytoplasm, cytoskeleton . Localizes to stereocilium tips in cochlear and vestibular hair cells. .
