- 产品信息
商品描述
靶点-Target
MADCA
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
42kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 260-340
特异性
MADCA Polyclonal Antibody detects endogenous levels of protein.
基因名称
MADCAM1
蛋白名称
Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) (hMAdCAM-1)
Organism-1
Human
基因ID-1
8174
SwissProt-1
Q13477
Organism-2
Mouse
SwissProt-2
Q61826
Organism-3
Rat
SwissProt-3
O70540
背景
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Membrane; Single-pass type I membrane protein.





