FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MUC4
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
238kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 1970-2050
特异性
MUC4 Polyclonal Antibody detects endogenous levels of protein.
基因名称
MUC4
蛋白名称
Mucin-4 (MUC-4) (Ascites sialoglycoprotein) (ASGP) (Pancreatic adenocarcinoma mucin) (Testis mucin) (Tracheobronchial mucin) [Cleaved into: Mucin-4 alpha chain (Ascites sialoglycoprotein 1) (ASGP-1); Mucin-4 beta chain (Ascites sialoglycoprotein 2) (ASGP-2)]
Organism-1
Human
基因ID-1
4585
SwissProt-1
Q99102
Organism-2
Mouse
SwissProt-2
Q8JZM8
Organism-3
Rat
SwissProt-3
Q63661
背景
The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats. [provided by RefSeq, Jul 2008],
细胞定位
[Mucin-4 beta chain]: Cell membrane ; Single-pass membrane protein . Isoforms lacking the Cys-rich region, EGF-like domains and transmembrane region are secreted. Secretion occurs by splicing or proteolytic processing. .; [Mucin-4 alpha chain]: Cell membrane . Secreted . Forms a complex with Mucin-4 beta chain at the cell membrane. .; [Isoform 3]: Cell membrane ; Single-pass membrane protein .; [Isoform 11]: Secreted .; [Isoform 15]: Secreted .; [Isoform 17]: Cell membrane ; Single-pass membrane protein .
