PDE7A Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2602935

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商品描述
  • 靶点-Target

    PDE7A

  • 反应性

    Human,Rat,Mouse

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    53kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:5000-20000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from part region of human protein

  • 特异性

    PDE7A Polyclonal Antibody detects endogenous levels of protein.

  • 基因名称

    PDE7A

  • 蛋白名称

    High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (HCP1) (TM22)

  • Organism-1

    Human

  • 基因ID-1

    5150

  • SwissProt-1

    Q13946

  • Organism-2

    Mouse

  • SwissProt-2

    P70453

  • Organism-3

    Rat

  • SwissProt-3

    O08593

  • 背景

    The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011],

  • 细胞定位

    [Isoform PDE7A1]: Cytoplasm, cytosol . PDE7A1 (57 kDa) is located mostly to soluble cellular fractions. .; [Isoform PDE7A2]: Cytoplasm . PDE7A2 (50 kDa) is located to particulate cellular fractions. .