- 产品信息
商品描述
靶点-Target
PDE7A
反应性
Human,Rat,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
53kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
PDE7A Polyclonal Antibody detects endogenous levels of protein.
基因名称
PDE7A
蛋白名称
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (HCP1) (TM22)
Organism-1
Human
基因ID-1
5150
SwissProt-1
Q13946
Organism-2
Mouse
SwissProt-2
P70453
Organism-3
Rat
SwissProt-3
O08593
背景
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011],
细胞定位
[Isoform PDE7A1]: Cytoplasm, cytosol . PDE7A1 (57 kDa) is located mostly to soluble cellular fractions. .; [Isoform PDE7A2]: Cytoplasm . PDE7A2 (50 kDa) is located to particulate cellular fractions. .





