- 产品信息
商品描述
靶点-Target
MCF2L
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
125kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
MCF2L Polyclonal Antibody detects endogenous levels of protein.
基因名称
MCF2L KIAA0362
蛋白名称
Guanine nucleotide exchange factor DBS (DBL's big sister) (MCF2-transforming sequence-like protein)
Organism-1
Human
基因ID-1
23263
SwissProt-1
O15068
Organism-2
Mouse
SwissProt-2
Q64096
Organism-3
Rat
SwissProt-3
Q63406
背景
This gene encodes a guanine nucleotide exchange factor that interacts specifically with the GTP-bound Rac1 and plays a role in the Rho/Rac signaling pathways. A variant in this gene was associated with osteoarthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
细胞定位
[Isoform 5]: Cytoplasm . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .; [Isoform 3]: Cytoplasm . Endomembrane system . Interaction with membranes enriched in phosphoinositides is mediated by the CRAL-TRIO domain. .; Cytoplasm . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .





