- 产品信息
商品描述
靶点-Target
GEPH
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
80kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
GEPH Polyclonal Antibody detects endogenous levels of protein.
基因名称
GPHN GPH KIAA1385
蛋白名称
Gephyrin [Includes: Molybdopterin adenylyltransferase (MPT adenylyltransferase) (Domain G); Molybdopterin molybdenumtransferase (MPT Mo-transferase) (Domain E)]
Organism-1
Human
基因ID-1
10243
SwissProt-1
Q9NQX3
Organism-2
Mouse
SwissProt-2
Q8BUV3
Organism-3
Rat
SwissProt-3
Q03555
背景
This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described; however, the full-length nature of all transcript variants is not currently known. [provided by RefSeq, Jul 2008],
细胞定位
Cell junction, synapse, postsynaptic cell membrane ; Lipid-anchor ; Cytoplasmic side . Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, cytosol . Cytoplasm, cytoskeleton . Cell projection, dendrite . Cell junction, synapse, postsynaptic density . Cytoplasmic face of glycinergic postsynaptic membranes (By similarity). Forms clusters at synapses (PubMed:25025157). .





