- 产品信息
商品描述
靶点-Target
DHB8
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
28kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
DHB8 Polyclonal Antibody detects endogenous levels of protein.
基因名称
HSD17B8 FABGL HKE6 RING2
蛋白名称
Estradiol 17-beta-dehydrogenase 8 (17-beta-hydroxysteroid dehydrogenase 8) (17-beta-HSD 8) (3-oxoacyl-[acyl-carrier-protein] reductase) (Protein Ke6) (Ke-6) (Really interesting new gene 2 protein) (Testosterone 17-beta-dehydrogenase 8) (EC 1.1.1.63)
Organism-1
Human
基因ID-1
7923
SwissProt-1
Q92506
Organism-2
Mouse
SwissProt-2
P50171
Organism-3
Rat
SwissProt-3
Q6MGB5
背景
hydroxysteroid 17-beta dehydrogenase 8(HSD17B8) Homo sapiens In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008],
细胞定位
Mitochondrion matrix .





