- 产品信息
商品描述
靶点-Target
EDEM3
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
102kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
EDEM3 Polyclonal Antibody detects endogenous levels of protein.
基因名称
EDEM3 C1orf22
蛋白名称
ER degradation-enhancing alpha-mannosidase-like 3
Organism-1
Human
基因ID-1
80267
SwissProt-1
Q9BZQ6
Organism-2
Mouse
SwissProt-2
Q2HXL6
背景
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008],
细胞定位
Endoplasmic reticulum lumen .





