- 产品信息
商品描述
靶点-Target
EDEM1
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
72kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
EDEM1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
EDEM1 EDEM KIAA0212
蛋白名称
ER degradation-enhancing alpha-mannosidase-like 1
Organism-1
Human
基因ID-1
9695
SwissProt-1
Q92611
Organism-2
Mouse
SwissProt-2
Q925U4
背景
function:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity.,similarity:Belongs to the glycosyl hydrolase 47 family.,subunit:Interacts with DERL2 and DERL3.,
细胞定位
Endoplasmic reticulum membrane ; Single-pass type II membrane protein .





