FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
HACE1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
99kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
HACE1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
HACE1 KIAA1320
蛋白名称
E3 ubiquitin-protein ligase HACE1 (HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1)
Organism-1
Human
基因ID-1
57531
SwissProt-1
Q8IYU2
Organism-2
Mouse
SwissProt-2
Q3U0D9
Organism-3
Rat
SwissProt-3
D3ZBM7
背景
This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016],
细胞定位
Golgi apparatus, Golgi stack membrane. Cytoplasm. Endoplasmic reticulum. A significant portion localizes to the endoplasmic reticulum. Targeted to Golgi membrane via its interaction with Rab proteins.
