- 产品信息
商品描述
靶点-Target
TOP1M
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
66kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
TOP1M Polyclonal Antibody detects endogenous levels of protein.
基因名称
TOP1MT
蛋白名称
DNA topoisomerase I, mitochondrial (TOP1mt) (EC 5.99.1.2)
Organism-1
Human
基因ID-1
116447
SwissProt-1
Q969P6
Organism-2
Mouse
SwissProt-2
Q8R4U6
Organism-3
Rat
SwissProt-3
Q6IM78
背景
This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],
细胞定位
Mitochondrion .





