- 产品信息
商品描述
靶点-Target
DOC11
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
228kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
DOC11 Polyclonal Antibody detects endogenous levels of protein.
基因名称
DOCK11 ZIZ2
蛋白名称
Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2)
Organism-1
Human
基因ID-1
139818
SwissProt-1
Q5JSL3
Organism-2
Mouse
SwissProt-2
A2AF47
背景
domain:The DHR-2 domain is necessary for the GEF activity.,function:Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the DOCK family.,similarity:Contains 1 DHR-1 (CZH-1) domain.,similarity:Contains 1 DHR-2 (CZH-2) domain.,similarity:Contains 1 PH domain.,subunit:Interacts with CDC42.,
细胞定位
intracellular,cytosol,





