- 产品信息
商品描述
靶点-Target
PDE5A
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
96kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
PDE5A Polyclonal Antibody detects endogenous levels of protein.
基因名称
PDE5A PDE5
蛋白名称
cGMP-specific 3',5'-cyclic phosphodiesterase (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)
Organism-1
Human
基因ID-1
8654
SwissProt-1
O76074
Organism-2
Mouse
SwissProt-2
Q8CG03
Organism-3
Rat
SwissProt-3
O54735
背景
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],
细胞定位
cytosol,





