- 产品信息
商品描述
靶点-Target
CHAC1
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
24kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
CHAC1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
CHAC1 BOTCH
蛋白名称
Cation transport regulator-like protein 1 (Blocks Notch protein) (Botch)
Organism-1
Human
基因ID-1
79094
SwissProt-1
Q9BUX1
Organism-2
Mouse
SwissProt-2
Q8R3J5
Organism-3
Rat
SwissProt-3
B3STU3
背景
This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016],
细胞定位
Cytoplasm, cytosol . Golgi apparatus, trans-Golgi network .





