FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
CAN6
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from part region of human protein
特异性
CAN6 Polyclonal Antibody detects endogenous levels of protein.
基因名称
CAPN6 CALPM CANPX
蛋白名称
Calpain-6 (Calpain-like protease X-linked) (Calpamodulin) (CalpM)
Organism-1
Human
基因ID-1
827
SwissProt-1
Q9Y6Q1
Organism-2
Mouse
SwissProt-2
O35646
Organism-3
Rat
SwissProt-3
O88501
背景
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. [provided by RefSeq, Nov 2009],
细胞定位
Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton, spindle . During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle.
