- 产品信息
商品描述
靶点-Target
PIF1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
70kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 150-230
特异性
PIF1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
PIF1 C15orf20
蛋白名称
ATP-dependent DNA helicase PIF1 (PIF1/RRM3 DNA helicase-like protein)
Organism-1
Human
基因ID-1
80119
SwissProt-1
Q9H611
Organism-2
Mouse
SwissProt-2
Q80SX8
Organism-3
Rat
SwissProt-3
Q1HG60
背景
This gene encodes a DNA-dependent adenosine triphosphate (ATP)-metabolizing enzyme that functions as a 5' to 3' DNA helicase. The encoded protein can resolve G-quadruplex structures and RNA-DNA hybrids at the ends of chromosomes. It also prevents telomere elongation by inhibiting the actions of telomerase. Alternative splicing and the use of alternative start codons results in multiple isoforms that are differentially localized to either the mitochondria or the nucleus. [provided by RefSeq, Nov 2013],
细胞定位
Nucleus .; [Isoform 4]: Mitochondrion .





