ANX11 Polyclonal Antibody

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2602622

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商品描述
  • 靶点-Target

    ANX11

  • 反应性

    Human,Mouse

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Observed)

    55kD

  • 推荐稀释比

    WB 1:500-2000;ELISA 1:5000-20000

  • 组成

    PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human protein . at AA range: 280-360

  • 特异性

    ANX11 Polyclonal Antibody detects endogenous levels of protein.

  • 基因名称

    ANXA11 ANX11

  • 蛋白名称

    Annexin A11 (56 kDa autoantigen) (Annexin XI) (Annexin-11) (Calcyclin-associated annexin 50) (CAP-50)

  • Organism-1

    Human

  • 基因ID-1

    311

  • SwissProt-1

    P50995

  • Organism-2

    Mouse

  • SwissProt-2

    P97384

  • 背景

    This gene encodes a member of the annexin family, a group of calcium-dependent phospholipid-binding proteins. Annexins have unique N-terminal domains and conserved C-terminal domains, which contain calcium-dependent phospholipid-binding sites. The encoded protein is a 56-kD antigen recognized by sera from patients with various autoimmune diseases. Several transcript variants encoding two different isoforms have been identified. [provided by RefSeq, Dec 2015],

  • 细胞定位

    Cytoplasm . Melanosome. Nucleus envelope. Nucleus, nucleoplasm . Cytoplasm, cytoskeleton, spindle. Found throughout the nucleoplasm at interphase and during mitosis concentrates around the mitotic apparatus (By similarity). Elevation of intracellular calcium causes relocalization from the nucleoplasm to the nuclear envelope, with little effect on the cytoplasmic pool. Localization to the nuclear envelope is cell-cycle dependent. .