- 产品信息
商品描述
靶点-Target
APBA1
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
92kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 180-260
特异性
APBA1 Polyclonal Antibody detects endogenous levels of protein.
基因名称
APBA1 MINT1 X11
蛋白名称
Amyloid beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1)
Organism-1
Human
基因ID-1
320
SwissProt-1
Q02410
Organism-2
Mouse
SwissProt-2
B2RUJ5
Organism-3
Rat
SwissProt-3
O35430
背景
amyloid beta precursor protein binding family A member 1(APBA1) Homo sapiens The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm . Cytoplasm, perinuclear region . Nucleus . Only about 5% of the protein is located in the nucleus.; [Isoform 2]: Golgi apparatus .





