FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
ALS2
反应性
Human,Mouse,Rat
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
182kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 390-470
特异性
ALS2 Polyclonal Antibody detects endogenous levels of protein.
基因名称
ALS2 ALS2CR6 KIAA1563
蛋白名称
Alsin (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 6 protein) (Amyotrophic lateral sclerosis 2 protein)
Organism-1
Human
基因ID-1
57679
SwissProt-1
Q96Q42
Organism-2
Mouse
SwissProt-2
Q920R0
Organism-3
Rat
SwissProt-3
P0C5Y8
背景
The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],
细胞定位
ruffle,early endosome,centrosome,cytosol,postsynaptic density,membrane,lamellipodium,axon,dendrite,growth cone,vesicle,neuronal cell body,dendritic spine,intracellular membra
