FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
AK1C4
反应性
Human
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Observed)
35kD
推荐稀释比
WB 1:500-2000;ELISA 1:5000-20000
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human protein . at AA range: 1-80
特异性
AK1C4 Polyclonal Antibody detects endogenous levels of protein.
基因名称
AKR1C4 CHDR
蛋白名称
Aldo-keto reductase family 1 member C4 (3-alpha-HSD1) (3-alpha-hydroxysteroid dehydrogenase type I) (Chlordecone reductase) (CDR) (Dihydrodiol dehydrogenase 4) (DD-4) (DD4) (HAKRA)
Organism-1
Human
基因ID-1
1109
SwissProt-1
P17516
背景
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytosol .
